Use of population PK/PD approach to model the thrombin generation assay: assessment in haemophilia A plasma samples spiked by a TFPI antibody

authors

  • Crépin Raphaël
  • Morin Claire
  • Montmartin Aurélie
  • Tardy-Poncet Brigitte
  • Chelle Pierre

keywords

  • Coagulation
  • Empirical model
  • Non-linear mixed-effects modelling
  • PK/PD model
  • Thrombin generation assay

document type

ART

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